Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15927445 | 0.81 | GSK3B (0.46) | GAAMAPTRAB9ANPC1TDP1 | |
| SCHEMBL8255295 | 0.77 | MAPT (0.38) | HPGDGAAMAPTRAB9ANPC1 | |
| SCHEMBL5662017 | 0.76 | ALDH1A1 (0.58) | HPGDSMN1; SMN2MCHR1MAPTRAB9A | |
| SCHEMBL21879204 | 0.76 | CTNNB1 (0.61) | HPGDSMN1; SMN2MCHR1MAPTRAB9A | |
| SCHEMBL23753567 | 0.75 | CNR1 (0.42) | HPGDSMN1; SMN2MCHR1MAPTRAB9A | |
| SCHEMBL6219159 | 0.74 | EPHX2 (0.40) | HPGDMAPTALDH1A1 | |
| SCHEMBL21318890 | 0.73 | MAPT (0.36) | HPGDGAAMAPTRAB9ANPC1 | |
| SCHEMBL5766935 | 0.73 | NOTUM (0.49) | MCHR1MAPTRAB9ANPC1 | |
| SCHEMBL4853275 | 0.73 | MCHR1 (0.59) | MCHR1MAPTCA12CA1CA2 | |
| SCHEMBL16716449 | 0.72 | CHRNB2 (0.51) | HPGDGAASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156311-A1 | PROCESSES FOR THE PREPARATION OF 1,2,3,5,6,7-HEXAHYDRO-S-INDACENE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-24 | — | — | WO | disclosed |