Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456082 | 0.81 | PDE4D (0.37) | MAPTNPC1RAB9AHPGDTDP1 | |
| SCHEMBL16526954 | 0.78 | NPC1 (0.32) | MAPTNPC1RAB9A | |
| SCHEMBL23519468 | 0.73 | HDAC8 (0.47) | MAPTHPGDALDH1A1 | |
| SCHEMBL16716449 | 0.73 | CHRNB2 (0.51) | MAPTNPC1RAB9AHPGDTDP1 | |
| SCHEMBL26317429 | 0.73 | HPGD (0.39) | MAPTNPC1RAB9AHPGDTDP1 | |
| SCHEMBL16527137 | 0.72 | ALDH1A1 (0.52) | MAPTNPC1RAB9AHPGDTDP1 | |
| SCHEMBL15927445 | 0.72 | GSK3B (0.46) | MAPTNPC1RAB9ATDP1GAA | |
| SCHEMBL25367450 | 0.72 | MAPT (0.33) | MAPTNPC1RAB9AHPGDTDP1 | |
| SCHEMBL13799411 | 0.71 | DRD2 (0.50) | MAPTNPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL16526961 | 0.71 | ALDH1A1 (0.50) | MAPTNPC1RAB9AHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247693-B1 | PROCESS FOR THE PREPARATION OF INDANAMINE DERIVATIVES AND NEW SYNTHESIS INTERMEDIATES | OLON SPA (IT) | 2019-09-04 | — | — | EP | disclosed |