Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18378884 | 0.76 | TGFBR1 (0.45) | TGFBR1ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL8781926 | 0.75 | DCPS (0.47) | TGFBR1ALDH1A1KDM4EHPGD | |
| SCHEMBL6464808 | 0.75 | LRRK2 (0.50) | MAP2K1SRCALDH1A1DYRK1A | |
| SCHEMBL8781923 | 0.75 | TGFBR1 (0.43) | TGFBR1ALDH1A1EGFRKDM4EHPGD | |
| SCHEMBL26317662 | 0.75 | TGFBR1 (0.45) | TGFBR1ALDH1A1KDM4EHPGD | |
| SCHEMBL22554335 | 0.75 | MAP2K1 (0.37) | MAP2K1TGFBR1ALDH1A1DYRK1AKDM4E | |
| SCHEMBL2202697 | 0.74 | SRC (0.59) | RAF1MAP2K1SRCEGFRERBB2 | |
| SCHEMBL23097812 | 0.72 | TGFBR1 (0.44) | TGFBR1ALDH1A1EGFRKDM4EHPGD | |
| SCHEMBL19957128 | 0.72 | MET (0.52) | SRCIMPDH2IMPDH1EGFRERBB2 | |
| SCHEMBL18368397 | 0.72 | TGFBR1 (0.41) | TGFBR1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | RAF1 227/4885MAP2K1 1163/4885SRC 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.