Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | ALPL | P05186 | 4/20 | 0.48 |
| ▸ | PLAA | Q9Y263 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258568 | 0.85 | ALPG (0.58) | ALPGMEN1KMT2APOLBALPL | |
| SCHEMBL10622910 | 0.79 | CYP1A2 (0.44) | ALPGMEN1KMT2APOLBALPL | |
| SCHEMBL7049792 | 0.79 | ALDH1A1 (0.50) | ALPGMEN1KMT2APOLBALPL | |
| SCHEMBL8680479 | 0.76 | HSD17B3 (0.51) | MEN1KMT2AMAPTHTTHDAC6 | |
| SCHEMBL11448472 | 0.76 | MCL1 (0.53) | ALPGMEN1KMT2APOLBALPL | |
| SCHEMBL10042364 | 0.75 | ALDH1A1 (0.50) | ALPGMEN1KMT2APOLBALPL | |
| SCHEMBL11631620 | 0.75 | KMT2A (0.59) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL10418143 | 0.75 | HDAC3 (0.62) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL1758255 | 0.74 | HTT (0.61) | POLBMAPTHTTSMN1; SMN2NPC1 | |
| SCHEMBL26320526 | 0.74 | ALDH1A1 (0.43) | ALPGMEN1KMT2AALPLPLAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPG 4545/4885MEN1 3170/4885KMT2A 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.