SCHEMBL394425

SCHEMBL394425

CC(C)(C)Cc1[c]cccc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.33
ESR1 P03372 1/20 0.32
SLC6A2 P23975 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
LMNA P02545 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27337058 0.83 SLC6A2 (0.48) SLC6A2TAAR1
SCHEMBL29020377 0.83 SLC6A2 (0.30) SLC6A2TAAR1
SCHEMBL2698490 0.83 SLC6A2 (0.30) SLC6A2TAAR1
SCHEMBL6893898 0.81
SCHEMBL9620893 0.79
SCHEMBL6893184 0.78 RIPK1 (0.34) RIPK1
SCHEMBL1071248 0.78
SCHEMBL263226 0.77
SCHEMBL9586177 0.77
SCHEMBL8042450 0.77 LMNA (0.40) RIPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220393118-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF CHE, CHI MING (CN) 2022-12-08 US claimed
CN-112552256-B Organic electroluminescent material and organic electroluminescent device using same 南京高光半导体材料有限公司 2022-10-25 CN claimed
CN-112442052-B High-efficiency and long-life blue fluorescent doped material, application thereof and organic electroluminescent device 南京高光半导体材料有限公司 2022-08-26 CN claimed
CN-112442053-B Blue fluorescent doping material with good thermal stability and high efficiency and organic electroluminescent device 南京高光半导体材料有限公司 2022-07-12 CN claimed
EP-4017936-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF Che, Chi Ming (HK) 2022-06-29 EP claimed
CN-112851649-A Organic electroluminescent compound containing multi-heterocyclic structure, organic electroluminescent device and application 南京高光半导体材料有限公司 2021-05-28 CN claimed
CN-112552256-A Organic electroluminescent material and organic electroluminescent device using same 南京高光半导体材料有限公司 2021-03-26 CN claimed
CN-112552255-A Organic electroluminescent material containing triphenylamine structure and organic electroluminescent device using same 南京高光半导体材料有限公司 2021-03-26 CN claimed
CN-112442053-A Blue fluorescent doping material with good thermal stability and high efficiency and organic electroluminescent device 南京高光半导体材料有限公司 2021-03-05 CN claimed
CN-112442052-A High-efficiency and long-life blue fluorescent doped material, application thereof and organic electroluminescent device 南京高光半导体材料有限公司 2021-03-05 CN claimed
CN-105186037-A Sulphonate stabilizer and non-aqueous electrolyte containing same UNIV CENTRAL SOUTH 2015-12-23 CN claimed
EP-2786985-A2 Antagonists of the glucagon receptor Metabasis Therapeutics, Inc. (US) 2014-10-08 EP claimed
CN-103904363-A Phosphite stabilizer and nonaqueous electrolyte containing same DONGGUAN SHANSHAN BATTERY MATERIALS CO LTD 2014-07-02 CN claimed
EP-2484685-A1 TRANSITION METAL COMPLEX, PREPARATION METHOD FOR SAID TRANSITION METAL COMPLEX, TRIMERIZATION CATALYST, PREPARATION METHOD FOR 1-HEXENE, PREPARATION METHOD FOR ETHYLENE POLYMER, SUBSTITUTED CYCLOPENTADIENE COMPOUND, AND PREPARATION METHOD FOR SAID SUBSTITUTED CYCLOPENTADIENE COMPOUND Sumitomo Chemical Co., Ltd (JP) 2012-08-08 EP claimed
US-20120184431-A1 TRANSITION METAL COMPLEX, PREPARATION METHOD FOR SAID TRANSITION METAL COMPLEX, TRIMERIZATION CATALYST, PREPARATION METHOD FOR 1-HEXENE, PREPARATION METHOD FOR ETHYLENE POLYMER, SUBSTITUTED CYCLOPENTADIENE COMPOUND, AND PREPARATION METHOD FOR SAID SUBSTITUTED CYCLOPENTADIENE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-19 US claimed
US-20100099875-A1 NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS PHOSPHOENIX SARL (FR) 2010-04-22 US claimed
EP-2129654-A1 NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR Metabasis Therapeutics, Inc. (US) 2009-12-09 EP claimed
WO-2008098244-A1 NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR METABASIS THERAPEUTICS, INC. (US) 2008-08-14 WO claimed
EP-1899358-A2 NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS Phosphoenix SARL (FR) 2008-03-19 EP claimed
WO-2006136695-A2 NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS PHOSPHOENIX SARL (FR) 2006-12-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099875-A1 NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS PNP, NANP, PHOSPHO1 RIPK1 3521/4885ESR1 1016/4885SLC6A2 3224/4885
US-20120184431-A1 TRANSITION METAL COMPLEX, PREPARATION METHOD FOR SAID TRANSITION METAL COMPLEX, TRIMERIZATION CATALYST, PREPARATION METHOD FOR 1-HEXENE, PREPARATION METHOD FOR ETHYLENE POLYMER, SUBSTITUTED CYCLOPENTADIENE COMPOUND, AND PREPARATION METHOD FOR SAID SUBSTITUTED CYCLOPENTADIENE COMPOUND EMC1, CYC1, AP1M1 RIPK1 1168/4885ESR1 272/4885SLC6A2 4843/4885
US-20220393118-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF PDCD2L, TTL, TTLL12 RIPK1 2962/4885ESR1 3300/4885SLC6A2 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.