SCHEMBL2632280

SCHEMBL2632280

Cc1nnc(-c2ccc(N3CCC(Oc4cc(F)ccc4Cl)CC3)nn2)o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCD O00767 5/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2622407 0.90 SCD (0.82) SCD
SCHEMBL12836448 0.85 SCD (0.73) SCD
SCHEMBL14870428 0.83 SCD (0.70) SCD
SCHEMBL31162759 0.82 SCD (0.70) SCD
SCHEMBL3467538 0.82 SCD (0.69) SCD
SCHEMBL4255462 0.81 SCD (0.68) SCD
SCHEMBL31162566 0.80 SCD (0.67) SCD
SCHEMBL4265657 0.80 SCD (0.67) SCD
SCHEMBL13777958 0.79 SCD (0.66) SCD
SCHEMBL4162084 0.79 SCD (0.65) SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250177367-A1 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION 2025-06-05 US claimed
CN-119677539-A Combination therapy for modulating lipid production 俄亥俄州创新基金会 2025-03-21 CN claimed
EP-4489865-A2 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION Ohio State Innovation Foundation (US) 2025-01-15 EP claimed
US-20240325385-A1 ANTI-TUMOR PHARMACEUTICAL COMPOSITION COMPRISING EZH2 INHIBITOR AND SCD1 INHIBITOR AND USE THEREOF PEKING UNIVERSITY THIRD HOSPITAL (CN) 2024-10-03 US claimed
WO-2023172669-A9 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2024-08-02 WO claimed
US-20230414626-A1 INDUCTION OF FERROPTOSIS FOR CANCER THERAPY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-12-28 US claimed
WO-2023172669-A2 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2023-09-14 WO claimed
CN-116568330-A Iron death induction for cancer treatment 纪念斯隆-凯特琳癌症中心 2023-08-08 CN claimed
WO-2023108563-A1 ANTI-TUMOR PHARMACEUTICAL COMPOSITION COMPRISING EZH2 INHIBITOR AND SD1 INHIBITOR AND USE THEREOF 北京大学第三医院(北京大学第三临床医学院) 2023-06-22 WO claimed
CN-115607547-A Modeling medicine for meibomian gland dysfunction animal model, construction method and application 厦门大学 2023-01-17 CN claimed
WO-2022093770-A1 COMBINATION THERAPY WITH PI3K-AKT-MTOR INHIBITORS AND FERROPTOSIS INDUCING AGENTS TO TREAT CANCER MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-05-05 WO claimed
WO-2022082078-A1 INDUCTION OF FERROPTOSIS FOR CANCER THERAPY MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-04-21 WO claimed
CN-114177299-A Antitumor pharmaceutical composition containing EZH2 inhibitor and SCD1 inhibitor and application thereof 北京大学第三医院(北京大学第三临床医学院) 2022-03-15 CN claimed
US-20210137934-A1 METHODS OF IDENTIFYING MYC-DRIVEN AND LIPOGENESIS-DEPENDENT NEOPLASMS AND METHODS OF TREATING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2021-05-13 US claimed
WO-2018170316-A1 METHODS OF IDENTIFYING MYC-DRIVEN AND LIPOGENESIS-DEPENDENT NEOPLASMS AND METHODS OF TREATING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2018-09-20 WO claimed
US-20180042925-A1 METHODS FOR TREATING CANCER CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2018-02-15 US claimed
US-20250367263-A9 Therapeutic Regimens and Methods for Treatment of Cardiovascular Risk Factors using a GLP-1R and GCGR Agonist SPITFIRE PHARMA LLC (US) 2025-12-04 US disclosed
US-20250334596-A1 ISOTOPIC LABELS FOR QUANTITATIVE MASS SPECTROMETRY OF LIPID ISOMERS TEXAS A & M UNIV SYS (US) 2025-10-30 US disclosed
US-20090239830-A1 Treatment of viral infections by modulation of host cell metabolic pathways KADMON CORPORATION, LLC 2009-09-24 US disclosed
WO-2009023059-A2 TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2009-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367263-A9 Therapeutic Regimens and Methods for Treatment of Cardiovascular Risk Factors using a GLP-1R and GCGR Agonist GLP1R, GCGR, GIPR SCD 145/4885
US-20090239830-A1 Treatment of viral infections by modulation of host cell metabolic pathways GOT2, MAVS, ME3 SCD 568/4885
US-20250177367-A1 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION ACACB, SREBF2, FASN SCD 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.