Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.68 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749134 | 0.85 | PNMT (0.64) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL633763 | 0.85 | PNMT (0.68) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL30606684 | 0.85 | PNMT (0.68) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL4910846 | 0.85 | PNMT (0.68) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7195192 | 0.84 | PNMT (0.72) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL5366733 | 0.84 | PNMT (0.72) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7603814 | 0.82 | PNMT (0.70) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL9859906 | 0.82 | PNMT (0.70) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7609046 | 0.82 | PNMT (0.70) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7607164 | 0.82 | PNMT (0.70) | PNMTDRD2DRD4DRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924154-A | Preparation method of piperidine-2-formate compound | 浙江九洲药业股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | claimed |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | claimed |
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | claimed |
| EP-4000623-A1 | 5-(2-(1H-INDOL-3-YL))-ETHYL)- PIPERAZIN-2-ONE DERIVATIVES FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY VIRUSES OF THE FAMILY CORONAVIRIDAE | Consejo Superior De Investigaciones Científicas (ES) | 2022-05-25 | — | — | EP | claimed |
| WO-2022101293-A1 | 5-(2-(1H-INDOL-3-YL))-ETHYL)- PIPERAZIN-2-ONE DERIVATIVES FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY VIRUSES OF THE FAMILY CORONAVIRIDAE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2022-05-19 | — | — | WO | claimed |
| CN-114106324-A | Polyamide acid solution and preparation method and application thereof | 吉林奥来德光电材料股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | claimed |
| WO-2020225700-A1 | COMPOUNDS HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF FOR THE CONTROL OF PHYTOPATHOGENIC FUNGI | ISAGRO S.P.A. (IT) | 2020-11-12 | — | — | WO | claimed |
| EP-3444265-B1 | PEPTIDE FOR SKIN REGENERATION OR WOUND TREATMENT AND USE THEREOF | KINE SCIENCES CO LTD (KR) | 2020-09-02 | — | — | EP | claimed |
| EP-0632026-A1 | Alpha amino acid derivatives, a method for their preparation and pharmaceutical preparations containing them | ADIR ET COMPAGNIE (FR) | 1995-01-04 | — | — | EP | claimed |
| EP-0406567-B1 | Process for the production of sulfonium compounds and novel methylthiophenol derivatives | MITSUBISHI GAS CHEMICAL CO (JP) | 1994-09-28 | — | — | EP | claimed |
| US-5159088-A | Photinitiators for cationic polymerization | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | claimed |
| EP-0245662-B1 | P-HYDROXYPHENYLSULFONIUM SALTS AND THEIR USE IN THE PREPARATION OF ESTERS AND AMIDES | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1991-08-07 | — | — | EP | claimed |
| EP-0406567-A2 | Process for the production of sulfonium compounds and novel methylthiophenol derivatives | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-01-09 | — | — | EP | claimed |
| EP-0375047-A2 | New process for the synthesis of N alpha-fluorenylmethoxycarbonyl-Ng-trityl-arginine | SCLAVO S.p.A. (IT) | 1990-06-27 | — | — | EP | claimed |
| EP-0346756-A1 | Process for production of sulfonium compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-12-20 | — | — | EP | claimed |
| EP-0331988-A1 | Sulfonium compounds, as well as process for producing active esters and amides used for the production of amides | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1989-09-13 | — | — | EP | claimed |
| US-4857656-A | Active esters used for production of esters or amides and process for producing esters or amides | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0245662-A1 | p-Hydroxyphenylsulfonium salts and their use in the preparation of esters and amides | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1987-11-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | PNMT 4164/4885DRD2 4609/4885DRD4 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.