Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HA1 | P13674 | 3/20 | 0.69 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.69 |
| ▸ | LDHA | P00338 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24049703 | 0.96 | P4HA1 (0.74) | P4HA1P4HTMLDHANPC1RAB9A | |
| SCHEMBL22332191 | 0.95 | P4HA1 (0.67) | P4HA1P4HTMLDHANPC1RAB9A | |
| SCHEMBL22332190 | 0.91 | P4HA1 (0.76) | P4HA1P4HTMLDHANPC1RAB9A | |
| SCHEMBL30633038 | 0.87 | P4HA1 (0.77) | P4HA1P4HTMLDHANPC1RAB9A | |
| SCHEMBL31084439 | 0.87 | P4HA1 (0.77) | P4HA1P4HTMLDHANPC1RAB9A | |
| SCHEMBL31486221 | 0.86 | LDHA (0.53) | P4HA1P4HTMLDHANPC1RAB9A | |
| SCHEMBL8521766 | 0.85 | LDHA (0.85) | P4HA1P4HTMLDHANPC1RAB9A | |
| SCHEMBL17114304 | 0.84 | P4HA1 (0.59) | P4HA1P4HTMLDHANPC1RAB9A | |
| SCHEMBL28312333 | 0.83 | LDHA (0.81) | P4HA1P4HTMLDHANPC1RAB9A | |
| SCHEMBL30753641 | 0.83 | LDHA (0.81) | P4HA1P4HTMLDHANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293698-A1 | METAL-ORGANIC FRAMEWORKS DELIVER SMALL MOLECULES AND BIOMACROMOLECULES FOR CANCER IMMUNOTHERAPY | UNIV CHICAGO (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293698-A1 | METAL-ORGANIC FRAMEWORKS DELIVER SMALL MOLECULES AND BIOMACROMOLECULES FOR CANCER IMMUNOTHERAPY | ORC3, RBM3, RNMT | P4HA1 4724/4885P4HTM 3500/4885LDHA 2148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.