Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105093 | 0.93 | ESR1 (0.52) | HSD17B1HSD17B2ESR1ESR2APP | |
| SCHEMBL12562762 | 0.93 | ESR1 (0.52) | HSD17B1HSD17B2ESR1ESR2APP | |
| SCHEMBL10100932 | 0.89 | ESR1 (0.55) | HSD17B1HSD17B2ESR1ESR2APP | |
| SCHEMBL23555830 | 0.83 | ESR1 (0.44) | HSD17B1HSD17B2ESR1ESR2APP | |
| SCHEMBL23555429 | 0.82 | ESR1 (0.43) | HSD17B1HSD17B2ESR1ESR2APP | |
| SCHEMBL20804567 | 0.79 | HSD17B1 (0.45) | HSD17B1HSD17B2ESR1ESR2MEN1 | |
| SCHEMBL20804592 | 0.79 | ESR1 (0.58) | HSD17B1HSD17B2ESR1ESR2APP | |
| SCHEMBL20662909 | 0.78 | RAB9A (0.45) | HSD17B1HSD17B2ESR1ESR2APP | |
| SCHEMBL20662908 | 0.78 | RAB9A (0.45) | HSD17B1HSD17B2ESR1ESR2APP | |
| SCHEMBL20804575 | 0.78 | ESR1 (0.61) | HSD17B1HSD17B2ESR1ESR2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | SONY CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | JUP, L1CAM, EPCAM | HSD17B1 4778/4885HSD17B2 4604/4885ESR1 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.