SCHEMBL263261

SCHEMBL263261

FC(F)(F)c1cccc(-n2c3ccc(-c4ccc5[nH]c6ccc(-c7ccc8c(c7)c7cc(C(F)(F)F)ccc7n8-c7cccc(C(F)(F)F)c7)cc6c5c4)cc3c3cc(C(F)(F)F)ccc32)c1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 8/20 0.51
CHUK O15111 1/20 0.43
GAA P10253 1/20 0.41
CYP1A2 P05177 1/20 0.40
KDM4E B2RXH2 1/20 0.39
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HTR1D P28221 1/20 0.39
HTR2C P28335 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
GSR P00390 1/20 0.38
PDPK1 O15530 1/20 0.38
PLA2G10 O15496 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262824 0.93 KIF11 (0.49) KIF11GAACYP1A2KDM4EALDH1A1
SCHEMBL262271 0.90 KIF11 (0.53) KIF11CHUKGAAKDM4EALDH1A1
SCHEMBL263065 0.88 KIF11 (0.51) KIF11CHUKCYP1A2KDM4EMAPT
SCHEMBL262960 0.88 KIF11 (0.51) KIF11CHUKCYP1A2KDM4EMAPT
SCHEMBL263081 0.88 KIF11 (0.56) KIF11CHUKGAAKDM4E
SCHEMBL262910 0.85 KIF11 (0.63) KIF11CHUKGAA
SCHEMBL263171 0.85 KIF11 (0.63) KIF11CHUKGAA
SCHEMBL263335 0.82 KIF11 (0.58) KIF11CHUKGAAKDM4E
SCHEMBL263039 0.82 KIF11 (0.51) KIF11CHUKGAAKDM4E
SCHEMBL11921066 0.81 KIF11 (0.64) KIF11CHUKKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8816098-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-26 US disclosed
US-8530672-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-10 US disclosed
US-20120309984-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-12-06 US disclosed
US-8278655-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-02 US disclosed
EP-1972619-B1 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LAB (JP) 2012-08-15 EP disclosed
US-20120104379-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-03 US disclosed
US-8134147-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-13 US disclosed
US-8134147-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-13 US disclosed
US-20100200847-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-08-12 US disclosed
US-20100200847-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-08-12 US disclosed
US-7723722-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-05-25 US disclosed
US-7723722-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-05-25 US disclosed
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-02 US disclosed
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-02 US disclosed
EP-1972619-A1 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104379-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE CYP1A1, XPO7, AMY1A KIF11 4217/4885CHUK 2864/4885GAA 754/4885
US-20120309984-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE CYP1A1, XPO7, AMY1A KIF11 4217/4885CHUK 2864/4885GAA 754/4885
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. CYP1A1, AADAT, AADAC KIF11 2940/4885CHUK 2242/4885GAA 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.