SCHEMBL26326658

SCHEMBL26326658

OC(c1ccc2ccccc2c1)C1CCCCC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.58
SLC6A4 P31645 1/20 0.58
SLC6A3 Q01959 1/20 0.58
MAPT P10636 1/20 0.57
UGT2B7 P16662 1/20 0.50
GABBR2 O75899 1/20 0.50
GABBR1 Q9UBS5 1/20 0.50
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
TSHR P16473 1/20 0.47
HIF1A Q16665 1/20 0.47
LMNA P02545 1/20 0.46
HTR1E P28566 1/20 0.46
HTT P42858 1/20 0.46
S1PR3 Q99500 1/20 0.46
DHODH Q02127 1/20 0.45
METAP2 P50579 2/20 0.44
AOC3 Q16853 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11356021 0.83 SLC6A4 (0.58) SLC6A2SLC6A4SLC6A3MAPTUGT2B7
SCHEMBL15345370 0.83 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3MAPTUGT2B7
Hydrochloric Acid SCHEMBL11359827 0.82 SLC6A4 (0.59) SLC6A2SLC6A4SLC6A3MAPTUGT2B7
SCHEMBL22314318 0.79 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAPTGABBR2
SCHEMBL29431468 0.79 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAPTGABBR2
SCHEMBL29431470 0.79 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAPTGABBR2
SCHEMBL3173810 0.78 HIF1A (0.64) SLC6A2SLC6A4SLC6A3MAPTMEN1
SCHEMBL1430742 0.77 IDO1 (0.53) MAPTMEN1KMT2ACYP1A2CYP2D6
SCHEMBL16995185 0.77 IDO1 (0.53) MAPTMEN1KMT2ACYP1A2CYP2D6
SCHEMBL477416 0.77 IDO1 (0.53) MAPTMEN1KMT2ACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-08-31 US disclosed
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE HPD, TALDO1, OGG1 SLC6A2 4398/4885SLC6A4 4230/4885SLC6A3 4352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.