Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1430742 | 1.00 | IDO1 (0.53) | IDO1DHODHKDM4ECYP1A2CYP2D6 | |
| SCHEMBL16995185 | 1.00 | IDO1 (0.53) | IDO1DHODHKDM4ECYP1A2CYP2D6 | |
| SCHEMBL477415 | 1.00 | IDO1 (0.53) | IDO1DHODHKDM4ECYP1A2CYP2D6 | |
| SCHEMBL8705439 | 0.98 | KDM4E (0.53) | IDO1DHODHKDM4ECYP1A2CYP2D6 | |
| SCHEMBL3310267 | 0.93 | CYP1A2 (0.53) | IDO1DHODHKDM4ECYP1A2CYP2D6 | |
| SCHEMBL477699 | 0.89 | CYP1A2 (0.56) | IDO1KDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL19645377 | 0.89 | CYP1A2 (0.56) | IDO1KDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL23652176 | 0.81 | HRH3 (0.45) | IDO1DHODHKDM4ECYP1A2CYP2D6 | |
| SCHEMBL8036930 | 0.81 | DHODH (0.56) | DHODHKDM4ETSHRKMT2AHRH3 | |
| SCHEMBL10021103 | 0.79 | DHODH (0.58) | IDO1DHODHCYP1A2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977368-A | A kind of synthetic method of optical voidness phenylcyclohexyl methanol | 康化（上海）新药研发有限公司 | 2017-07-25 | — | — | CN | claimed |
| EP-1042291-B1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE CO CHEM PHARM FAB (DE) | 2005-07-13 | — | — | EP | claimed |
| JP-6032813-A | — | — | None | — | — | JP | disclosed |
| US-11866430-B2 | Naphthyridinone compounds useful as T cell activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-09 | — | — | US | disclosed |
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
| EP-3814347-B1 | NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-05-03 | — | — | EP | disclosed |
| EP-3814347-B1 | NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-05-03 | — | — | EP | disclosed |
| WO-2023016459-A1 | NOVEL ORGANIC ALKOXIDE AGGLOMERATE, AND PREPARATION METHOD THEREFOR AND APPLICATION AND THEREOF | 上海科技大学 | 2023-02-16 | — | — | WO | disclosed |
| CN-109627152-B | Photocatalytic synthesis method and application of cyclohexyl- (4-R phenyl) ketone compound | 甘肃金盾化工有限责任公司 | 2022-01-25 | — | — | CN | disclosed |
| EP-0847988-A1 | Process for the preparation of N-hydrocarbyl-substituted amides | The Lubrizol Corporation (US) | 1998-06-17 | — | — | EP | disclosed |
| EP-0846678-A1 | Process for the preparation of N-hydrocarbyl-substituted amides | The Lubrizol Corporation (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5712413-A | Process for the preparation of N-hydrocarbyl-substituted amides such as tert-butylacrylamide via the Ritter reaction using solid heteropolyacid catalysts | THE LUBRIZOL CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0686635-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| JP-H0632813-A | POLYMERIZATION INITIATOR COMPOSITION | THREE BOND CO LTD | 1994-02-08 | — | — | JP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |
| EP-0549364-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | HPD, TALDO1, OGG1 | IDO1 2029/4885DHODH 313/4885KDM4E 1084/4885 |
| US-11866430-B2 | Naphthyridinone compounds useful as T cell activators | DGKZ, DGKA, DGKG | IDO1 1965/4885DHODH 557/4885KDM4E 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.