Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477557 | 0.90 | UGT2B7 (0.61) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL477559 | 0.90 | UGT2B7 (0.61) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL30161628 | 0.90 | UGT2B7 (0.61) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL600527 | 0.88 | UGT2B7 (0.68) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL30033673 | 0.88 | UGT2B7 (0.68) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL12405817 | 0.84 | UGT2B7 (0.53) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3585861 | 0.83 | CA12 (0.59) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL4504963 | 0.81 | CA1 (0.62) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL26326655 | 0.81 | UGT2B7 (0.55) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL26326654 | 0.81 | UGT2B7 (0.60) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | HPD, TALDO1, OGG1 | UGT2B7 300/4885SLC6A2 4398/4885SLC6A4 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.