SCHEMBL263267

SCHEMBL263267

CCc1[c]c(CC)cc(C)c1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27903407 0.88 TPMT (0.30)
SCHEMBL466431 0.87 NOS3 (0.31) NOS3NOS2
Lithium Ion SCHEMBL752492 0.84
SCHEMBL456834 0.83
SCHEMBL457435 0.83
SCHEMBL9139369 0.79 TP53 (0.41) TSHRRAPGEF4
SCHEMBL456298 0.79 ACHE (0.37)
SCHEMBL1780256 0.78 NOS2 (0.39) NOS3NOS2ALDH1A1
SCHEMBL457229 0.78
SCHEMBL509320 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114423739-B Improved enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines in the presence of chiral iridium catalysts and additives 拜耳公司 2024-06-25 CN claimed
CN-114514223-B Process for enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines comprising using novel iridium catalysts 拜耳公司 2024-05-17 CN claimed
CN-111902399-B Enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines in the presence of chiral iridium catalysts 拜耳公司 2023-11-28 CN claimed
WO-2023172667-A2 SUBSTITUTED IMIDAZO[1,5-a]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-09-14 WO claimed
EP-3774735-B1 ENANTIOSELECTIVE HYDROGENATION OF 4-SUBSTITUTED 1,2-DIHYDROQUINOLINES IN PRESENCE OF A CHIRAL IRIDIUM CATALYST BAYER AG (DE) 2023-09-13 EP claimed
CN-116693734-A Preparation method and application of trans-1, 2-poly-ocimene 湖北航天化学技术研究所 2023-09-05 CN claimed
CN-116693733-A Isotactic cis-1, 4-poly-ocimene and preparation method and application thereof 中国科学院长春应用化学研究所 2023-09-05 CN claimed
CN-116554372-A Preparation method of low-entanglement ultra-high molecular weight polyethylene 中国科学院长春应用化学研究所 2023-08-08 CN claimed
EP-4034528-A1 PROCESS COMPRISING THE USE OF NEW IRIDIUM CATALYSTS FOR ENANTIOSELECTIVE HYDROGENATION OF 4-SUBSTITUTED 1,2-DIHYDROQUINOLINES Bayer Aktiengesellschaft (DE) 2022-08-03 EP claimed
CN-114514223-A Process comprising enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines using a novel iridium catalyst 拜耳公司 2022-05-17 CN claimed
EP-2289949-A1 ISOPRENE OR BUTADIENE CIS 1,4-POLYMERIC BI-COMPONENT CATALYST SYSTEM AND POLYMERIZATION PROCESS Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) 2011-03-02 EP claimed
US-20100286350-A1 BI-COMPONENT CATALYST SYSTEM FOR ISOPRENE OR BUTADIENE CIS 1, 4-POLYMERIZATION AND POLYMERIZATION PROCESS CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2010-11-11 US claimed
US-20080139830-A1 Preparation of substituted aminoanthraquinones LANXESS DEUTSCHLAND GMBH 2008-06-12 US claimed
EP-1930377-A2 Method for producing substituted aminoanthraquinones Lanxess Deutschland GmbH (DE) 2008-06-11 EP claimed
EP-0797774-A1 MULTILAYER ANALYTICAL ELEMENT 2860601 Canada Inc. (CN) 1997-10-01 EP claimed
WO-1996018898-A1 MULTILAYER ANALYTICAL ELEMENT 2860601 CANADA INC. (CA) 1996-06-20 WO claimed
EP-0312019-B1 CONDENSED HETEROCYCLIC COMPOUNDS, A PROCESS FOR PREPARING THE SAME AND A HERBICIDAL COMPOSITION THEREOF DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1993-08-04 EP claimed
US-4936121-A Condensed heterocyclic compounds, a process for preparing the same and a herbicidal composition thereof DAICEL CHEMICAL INDUSTRIES LTD. (JP) 1990-06-26 US claimed
EP-0312019-A2 Condensed heterocyclic compounds, a process for preparing the same and a herbicidal composition thereof DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-19 EP claimed
US-4585574-A POSITIVE DIELECTRIC ANISOTROPY BAYER AKTIENGESELLSCHAFT (DE) 1986-04-29 US claimed