Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GALR1 | P47211 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21256817 | 0.84 | FYN (0.45) | KMT2ANPC1RAB9AEHMT2 | |
| SCHEMBL26326796 | 0.81 | NPC1 (0.47) | TDP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8704325 | 0.75 | TP53 (0.49) | TDP1KMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8704174 | 0.73 | TP53 (0.48) | TDP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1240839 | 0.71 | GALR1 (0.59) | TDP1PI4KBKMT2AMEN1HTR2C | |
| Hydrochloric Acid SCHEMBL8707793 | 0.70 | NPC1 (0.41) | TDP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL14220732 | 0.70 | NPC1 (0.58) | TDP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1240799 | 0.69 | GALR1 (0.44) | TDP1PI4KBKMT2AMEN1HTR2C | |
| SCHEMBL5358992 | 0.68 | ABCB1 (0.45) | TDP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL21256849 | 0.68 | FYN (0.42) | KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767316-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767316-B2 | Non-fused thiophene derivatives and their uses | FTH1, SLC40A1, FECH | TDP1 1840/4885PI4KB 1208/4885KMT2A 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.