Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | PDE6A | P16499 | 1/20 | 0.39 |
| ▸ | PDE6G | P18545 | 1/20 | 0.39 |
| ▸ | PDE6B | P35913 | 1/20 | 0.39 |
| ▸ | PDE6C | P51160 | 1/20 | 0.39 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21256817 | 0.83 | FYN (0.45) | FYNKMT2APDE6DPDE6APDE6G | |
| SCHEMBL21259105 | 0.71 | CNR2 (0.44) | ALDH1A1 | |
| SCHEMBL28373126 | 0.69 | ALDH1A1 (0.58) | ALDH1A1TSHRFDPS | |
| SCHEMBL7361245 | 0.69 | ALDH1A1 (0.58) | ALDH1A1TSHRFDPS | |
| SCHEMBL22965291 | 0.69 | KMT2A (0.45) | FYNKMT2AKDM1ANPC1RAB9A | |
| SCHEMBL21259117 | 0.69 | KCNH3 (0.46) | — | |
| SCHEMBL8236716 | 0.68 | ALDH1A1 (0.45) | ALDH1A1TSHRKMT2AFDPSSMN1; SMN2 | |
| SCHEMBL26326821 | 0.68 | TDP1 (0.46) | KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14837620 | 0.66 | LMNA (0.50) | ALDH1A1TSHRKMT2AFDPSSMN1; SMN2 | |
| SCHEMBL23759728 | 0.66 | POLB (0.44) | FYNPDE6DPDE6APDE6GPDE6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154956-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |