Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672467 | 0.82 | HCAR2 (0.40) | HCAR2ALDH1A1LMNATSHRCHRM1 | |
| SCHEMBL27984406 | 0.82 | HCAR2 (0.40) | HCAR2ALDH1A1LMNATSHRCHRM1 | |
| SCHEMBL20704238 | 0.80 | HCAR2 (0.39) | HCAR2ALDH1A1LMNATSHRCHRM1 | |
| SCHEMBL204763 | 0.79 | POLB (0.44) | HCAR2ALDH1A1LMNATSHRCHRM1 | |
| SCHEMBL6062638 | 0.79 | HCAR2 (0.41) | HCAR2ALDH1A1LMNATSHRCHRM1 | |
| SCHEMBL2251744 | 0.78 | HCAR2 (0.38) | HCAR2ALDH1A1LMNATSHRCHRM1 | |
| SCHEMBL14152314 | 0.78 | HCAR2 (0.38) | HCAR2ALDH1A1LMNATSHRCHRM1 | |
| SCHEMBL5491673 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRATMKDM4E | |
| SCHEMBL5610701 | 0.77 | HCAR2 (0.45) | HCAR2ALDH1A1LMNATSHRCHRM1 | |
| SCHEMBL5611304 | 0.77 | HCAR2 (0.40) | HCAR2ALDH1A1LMNATSHRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | HCAR2 4099/4885ALDH1A1 1805/4885LMNA 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.