SCHEMBL26327396

SCHEMBL26327396

N#C[C@@]1(c2ccc3c(N)ncnn23)O[C@H](CCOP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.85

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.49
▸ TMPRSS2 O15393 1/20 0.45
▸ P2RX1 P51575 2/20 0.36
▸ P2RX3 P56373 2/20 0.36
▸ P2RX2 Q9UBL9 1/20 0.36
▸ P2RX4 Q99571 1/20 0.36
▸ RNASEL Q05823 1/20 0.36
▸ P2RY2 P41231 2/20 0.34
▸ P2RY1 P47900 1/20 0.34
▸ P2RY11 Q96G91 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rdv-Tp SCHEMBL26003192 0.92 POLRMT (0.51) POLRMTTMPRSS2P2RX1P2RX3P2RX2
Rdv-Tp SCHEMBL24492746 0.92 POLRMT (0.51) POLRMTTMPRSS2P2RX1P2RX3P2RX2
Rdv-Tp SCHEMBL10120881 0.92 POLRMT (0.51) POLRMTTMPRSS2P2RX1P2RX3P2RX2
Rdv-Tp SCHEMBL24492745 0.92 POLRMT (0.51) POLRMTTMPRSS2P2RX1P2RX3P2RX2
Rdv-Tp SCHEMBL23278555 0.92 POLRMT (0.51) POLRMTTMPRSS2P2RX1P2RX3P2RX2
SCHEMBL17719238 0.90 POLRMT (0.48) POLRMTTMPRSS2P2RX1P2RX3P2RX2
SCHEMBL15998264 0.86 TMPRSS2 (0.46) POLRMTTMPRSS2P2RX1P2RX3P2RX2
SCHEMBL26753688 0.86 TMPRSS2 (0.48) POLRMTTMPRSS2P2RX1P2RX3P2RX2
SCHEMBL26753667 0.86 TMPRSS2 (0.46) POLRMTTMPRSS2P2RX1P2RX3P2RX2
SCHEMBL881568 0.85 POLRMT (0.49) POLRMTTMPRSS2P2RX1P2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287029-A1 ANTIVIRAL PRODRUGS, PHARMACEUTICAL FORMULATIONS, AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-09-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287029-A1 ANTIVIRAL PRODRUGS, PHARMACEUTICAL FORMULATIONS, AND METHODS MTAP, SARS1, RNGTT POLRMT 20/4885TMPRSS2 181/4885P2RX1 280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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