SCHEMBL26753667

SCHEMBL26753667

N#C[C@@]1(c2ccc3c(N)ncnn23)O[C@H](CSP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.78

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.46
▸ POLRMT O00411 1/20 0.45
▸ P2RY2 P41231 1/20 0.33
▸ P2RX1 P51575 2/20 0.32
▸ P2RX3 P56373 2/20 0.32
▸ P2RX2 Q9UBL9 1/20 0.32
▸ ENTPD1 P49961 2/20 0.32
▸ P2RX4 Q99571 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rdv-Tp SCHEMBL24492745 0.88 POLRMT (0.51) TMPRSS2POLRMTP2RX1P2RX3P2RX2
Rdv-Tp SCHEMBL26003192 0.88 POLRMT (0.51) TMPRSS2POLRMTP2RX1P2RX3P2RX2
Rdv-Tp SCHEMBL10120881 0.88 POLRMT (0.51) TMPRSS2POLRMTP2RX1P2RX3P2RX2
Rdv-Tp SCHEMBL23278555 0.88 POLRMT (0.51) TMPRSS2POLRMTP2RX1P2RX3P2RX2
Rdv-Tp SCHEMBL24492746 0.88 POLRMT (0.51) TMPRSS2POLRMTP2RX1P2RX3P2RX2
SCHEMBL17719238 0.87 POLRMT (0.48) TMPRSS2POLRMTP2RX1P2RX3P2RX2
SCHEMBL26753688 0.87 TMPRSS2 (0.48) TMPRSS2POLRMTP2RY2P2RX1P2RX3
SCHEMBL15998264 0.87 TMPRSS2 (0.46) TMPRSS2POLRMTP2RY2P2RX1P2RX3
SCHEMBL26327396 0.86 POLRMT (0.49) TMPRSS2POLRMTP2RY2P2RX1P2RX3
SCHEMBL17719237 0.84 TMPRSS2 (0.50) TMPRSS2POLRMTP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355649-A1 FORMULATIONS OF ANTI-VIRAL COMPOUNDS SAYVAA PHARMACEUTICALS INC. 2023-11-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355649-A1 FORMULATIONS OF ANTI-VIRAL COMPOUNDS SARS1, RNMT, NSUN2 TMPRSS2 1436/4885POLRMT 53/4885P2RY2 4587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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