SCHEMBL26327407

SCHEMBL26327407

Cc1cc(Cl)c(C)c(-c2ccc(Cl)c(C)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.43
PTGS1 P23219 2/20 0.42
AHR P35869 4/20 0.36
BRD4 O60885 1/20 0.36
CREBBP Q92793 1/20 0.36
ALKBH3 Q96Q83 1/20 0.36
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
RAPGEF4 Q8WZA2 3/20 0.34
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
ABL1 P00519 1/20 0.33
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4300888 0.76 AHR (0.55) PTGS2PTGS1AHRPDE3BPDE3A
SCHEMBL29473772 0.76 CYP2A6 (0.46) PTGS1
SCHEMBL28598819 0.76 CYP2A6 (0.46) PTGS1
SCHEMBL16168616 0.73 AHR (0.46) PTGS2PTGS1AHRPDE3BPDE3A
SCHEMBL24720587 0.72 ESR2 (0.47) PTGS2PTGS1AHRALKBH3AKR1C3
SCHEMBL21508017 0.72 ALKBH3 (0.42) PTGS2PTGS1ALKBH3AKR1C3AKR1C2
SCHEMBL16574090 0.71 MAP4K4 (0.49) PTGS2PTGS1AHRABL1
SCHEMBL1004002 0.68 ACHE (0.40) RAPGEF4
SCHEMBL29144519 0.68 PTGS2 (0.42) PTGS2PTGS1AHRBRD4CREBBP
SCHEMBL9601318 0.67 AHR (0.43) AHRALKBH3RAPGEF4AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023156482-A1 THERMOSTABLE PHOTOPOLYMERS IN THE VISIBLE SPECTRAL RANGE AND PHOTOPOLYMER COMPOSITIONS CONTAINING SAME COVESTRO DEUTSCHLAND AG (DE) 2023-08-24 WO disclosed