Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30775235 | 0.78 | MAPK1 (0.49) | CYP3A4CYP2D6CYP2C19SIGMAR1MAPK1 | |
| SCHEMBL24875813 | 0.74 | SIGMAR1 (0.44) | CYP3A4CYP2D6CYP2C19SIGMAR1MAPK1 | |
| SCHEMBL20670974 | 0.72 | SMN1; SMN2 (0.45) | CD274MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL22516756 | 0.71 | SIGMAR1 (0.45) | CYP3A4CYP2D6CYP2C19SIGMAR1MAPK1 | |
| SCHEMBL20660530 | 0.70 | KMT2A (0.48) | CYP2C19CD274ALDH1A1MEN1KMT2A | |
| SCHEMBL20660927 | 0.69 | ALDH1A1 (0.44) | CYP2C19CD274SIGMAR1ALDH1A1KCNH2 | |
| SCHEMBL30875134 | 0.69 | ALDH1A1 (0.43) | CYP2C19CD274ALDH1A1KMT2AKDM4E | |
| SCHEMBL21266801 | 0.67 | NPC1 (0.41) | SIGMAR1CHRM1POLBNPC1RAB9A | |
| SCHEMBL8178868 | 0.67 | TAS2R8 (0.43) | MKNK1MAPK1TYK2 | |
| Hydrochloric Acid SCHEMBL3257525 | 0.66 | TAS2R8 (0.43) | MKNK1MAPK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164057-A1 | DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-08-31 | — | — | WO | disclosed |