Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11396618 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TET2EGLN1TSHRPOLB | |
| SCHEMBL11396616 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TET2EGLN1TSHRPOLB | |
| SCHEMBL13547462 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TET2EGLN1POLBPKM | |
| SCHEMBL3279705 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TET2EGLN1KEAP1NFE2L2 | |
| SCHEMBL23774695 | 0.73 | — | — | |
| SCHEMBL17272640 | 0.73 | ALDH1A1 (0.39) | ALDH1A1TET2EGLN1KEAP1NFE2L2 | |
| SCHEMBL346841 | 0.73 | — | — | |
| SCHEMBL346842 | 0.73 | — | — | |
| SCHEMBL6950834 | 0.71 | ALDH1A1 (0.56) | ALDH1A1TET2EGLN1KEAP1NFE2L2 | |
| SCHEMBL8295 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | ALDH1A1 1805/4885TET2 120/4885EGLN1 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.