Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25440304 | 0.78 | HSD17B10 (0.40) | HSD17B10HTTHSP90AB1TSHRCYP4F2 | |
| SCHEMBL21557857 | 0.77 | HSP90AB1 (0.42) | HSD17B10HTTHSP90AB1TSHRCYP4F2 | |
| SCHEMBL22016826 | 0.73 | HTT (0.52) | HTTCA2ALDH1A1L3MBTL1 | |
| SCHEMBL12457570 | 0.71 | HSP90AB1 (0.41) | HSD17B10HTTHSP90AB1TSHRCYP4F2 | |
| SCHEMBL11714467 | 0.70 | HSP90AB1 (0.44) | HSD17B10HTTHSP90AB1TSHRCYP4F2 | |
| SCHEMBL19268378 | 0.69 | CA12 (0.69) | HSD17B10HTTCA12CA1CA2 | |
| SCHEMBL4651342 | 0.69 | ALDH1A1 (0.51) | HSD17B10ALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL16425168 | 0.68 | HSD17B10 (0.39) | HSD17B10HTTHSP90AB1ALDH1A1KDM4E | |
| SCHEMBL13807578 | 0.68 | MAPT (0.42) | HSD17B10HTTHSP90AB1CA12CA1 | |
| SCHEMBL13799643 | 0.67 | KDM4E (0.41) | HSD17B10HTTHSP90AB1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | TST, CYP4F8, CYP4Z1 | HSD17B10 616/4885HTT 1626/4885HSP90AB1 4642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.