Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | FGF2 | P09038 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26196517 | 0.89 | ALDH1A1 (0.43) | ALDH1A1HTTPOLBMGLLSMN1; SMN2 | |
| SCHEMBL17574699 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTPOLBMGLLSMN1; SMN2 | |
| SCHEMBL26234021 | 0.76 | MGLL (0.71) | ALDH1A1HTTMGLLSMN1; SMN2HPGD | |
| SCHEMBL9908375 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTPOLBMGLLSMN1; SMN2 | |
| SCHEMBL26196511 | 0.76 | HTT (0.40) | ALDH1A1HTTPOLBMGLLSMN1; SMN2 | |
| SCHEMBL17190593 | 0.76 | LMNA (0.39) | ALDH1A1POLBMGLLMEN1KMT2A | |
| SCHEMBL26695483 | 0.76 | MGLL (0.47) | ALDH1A1HTTPOLBMGLLSMN1; SMN2 | |
| SCHEMBL24478565 | 0.75 | MGLL (0.37) | ALDH1A1HTTPOLBMGLLSMN1; SMN2 | |
| SCHEMBL19761999 | 0.75 | PIK3CD (0.49) | POLBMEN1KMT2A | |
| SCHEMBL4741521 | 0.75 | LMNA (0.38) | ALDH1A1POLBMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023170608-A1 | ACTIVATORS OF EFFECTOR T CELLS | ORUM THERAPEUTICS, INC. (KR) | 2023-09-14 | — | — | WO | disclosed |