Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13326331 | 0.93 | ALDH1A1 (0.46) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL2633133 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL12948863 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL22139741 | 0.88 | KDM4E (0.45) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL22170182 | 0.88 | KDM4E (0.44) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL10076374 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL15654259 | 0.86 | CYP2D6 (0.46) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL8572905 | 0.86 | PRKCH (0.43) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL16745455 | 0.86 | BCHE (0.45) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL2627650 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100555-A1 | Synthesis And Use Of Fluorophore-Tagged Antimalarials | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100555-A1 | Synthesis And Use Of Fluorophore-Tagged Antimalarials | ABCC1, DHFR, GFPT1 | KDM4E 850/4885ALDH1A1 1296/4885GLA 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.