Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 2/20 | 0.56 |
| ▸ | CPA2 | P48052 | 2/20 | 0.56 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632702 | 0.92 | CPA1 (0.55) | CPA1CPA2CPA4ALDH1A1CTSL | |
| SCHEMBL2633273 | 0.86 | CTSL (0.51) | CTSLBIRC2CAPN1MMP3 | |
| SCHEMBL2632695 | 0.86 | CPA1 (0.62) | CPA1CPA2CPA4ALDH1A1MMP12 | |
| SCHEMBL2735610 | 0.85 | PSMB5 (0.52) | CPA1CPA2CPA4ALDH1A1CTSL | |
| SCHEMBL8972583 | 0.84 | ALDH1A1 (0.64) | CPA1CPA2CPA4ALDH1A1BIRC2 | |
| SCHEMBL12563719 | 0.84 | ALDH1A1 (0.64) | CPA1CPA2CPA4ALDH1A1BIRC2 | |
| SCHEMBL2735640 | 0.84 | CTSL (0.55) | CPA1CPA2CPA4CTSLMMP3 | |
| SCHEMBL2632703 | 0.84 | CPA1 (0.61) | CPA1CPA2CPA4ALDH1A1CTSL | |
| SCHEMBL17948648 | 0.84 | CPA1 (0.63) | CPA1CPA2CPA4ALDH1A1TMPRSS11D | |
| SCHEMBL14208695 | 0.84 | CTSL (0.56) | CPA1CPA2CPA4ALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101026-A1 | Compounds For Enzyme Inhibition | ONYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101026-A1 | Compounds For Enzyme Inhibition | ANPEP, DNPEP, CPN1 | CPA1 161/4885CPA2 264/4885CPA4 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.