⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21547350 | 0.84 | TTR (0.33) | — | |
| SCHEMBL26334547 | 0.81 | TTR (0.31) | — | |
| SCHEMBL13236292 | 0.77 | HRH3 (0.35) | — | |
| SCHEMBL26334549 | 0.72 | TTR (0.32) | — | |
| SCHEMBL4730144 | 0.69 | APEX1 (0.30) | — | |
| SCHEMBL12305002 | 0.69 | HTR1D (0.41) | — | |
| SCHEMBL1336793 | 0.68 | TTR (0.36) | — | |
| SCHEMBL15262205 | 0.68 | TTR (0.36) | — | |
| SCHEMBL31488013 | 0.67 | HTR1D (0.37) | — | |
| SCHEMBL8986777 | 0.67 | CA2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331745-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK AS (DK) | 2023-10-19 | — | — | US | disclosed |
| US-11767332-B2 | Glucose-sensitive albumin-binding derivatives | NOVO NORDISK A/S (DK) | 2023-09-26 | — | — | US | disclosed |