Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232970 | 0.77 | TDP1 (0.43) | — | |
| SCHEMBL25312299 | 0.72 | MAPT (0.34) | — | |
| SCHEMBL28013373 | 0.72 | APEX1 (0.56) | APEX1 | |
| SCHEMBL16180654 | 0.69 | APEX1 (0.37) | APEX1 | |
| SCHEMBL26334545 | 0.69 | — | — | |
| SCHEMBL6643677 | 0.69 | ALDH1A1 (0.48) | — | |
| SCHEMBL2925270 | 0.69 | ACHE (0.40) | — | |
| SCHEMBL26334547 | 0.67 | TTR (0.31) | — | |
| SCHEMBL7192729 | 0.67 | IDO1 (0.34) | — | |
| SCHEMBL26630683 | 0.67 | TTR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053158-A1 | INHIBITORS OF P38 MITOGEN-ACTIVATED PROTEIN KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008053158-A1 | INHIBITORS OF P38 MITOGEN-ACTIVATED PROTEIN KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |