SCHEMBL26334549

SCHEMBL26334549

Cc1cc(I)cc(Br)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1336793 0.86 TTR (0.36) TTR
SCHEMBL12379160 0.80 TTR (0.40) TTR
SCHEMBL31568142 0.75 AHR (0.30)
SCHEMBL12130275 0.75
SCHEMBL15262205 0.75 TTR (0.36) TTRALDH1A1
SCHEMBL459156 0.72 RAPGEF4 (0.39) ALDH1A1CYP1A2
SCHEMBL5780229 0.72 AHR (0.44) ALDH1A1CYP1A2
SCHEMBL10068236 0.72 TTR (0.48) TTR
SCHEMBL25584158 0.72
SCHEMBL26334545 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331745-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2023-10-19 US disclosed
US-11767332-B2 Glucose-sensitive albumin-binding derivatives NOVO NORDISK A/S (DK) 2023-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331745-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES ALB, DBI, FABP4 TTR 186/4885ALDH1A1 1240/4885CYP1A2 3198/4885
US-11767332-B2 Glucose-sensitive albumin-binding derivatives ALB, DBI, FABP4 TTR 186/4885ALDH1A1 1240/4885CYP1A2 3198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.