SCHEMBL263371

SCHEMBL263371

CC(=O)C1(Cl)CCOC1=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
CYP2C9 P11712 3/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 2/20 0.33
CYP2C19 P33261 2/20 0.33
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9099166 0.88 ALDH1A1 (0.31) ALDH1A1
SCHEMBL28544357 0.76
SCHEMBL4252207 0.72 CYP2C9 (0.41) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL7517029 0.72 CYP2C9 (0.41) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL8990312 0.71 ALDH1A1 (0.35) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL17199882 0.71 ALDH1A1 (0.35) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL10247874 0.70 SMN1; SMN2 (0.42) ALDH1A1
SCHEMBL4895573 0.69 ALDH1A1 (0.35) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL8593083 0.68 ALDH1A1 (0.34) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL981063 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222586523-U Reaction device for continuously preparing 3, 5-dichloro-2-pentanone 河北诚信集团有限公司 2025-03-11 CN claimed
CN-119552133-A Process for synthesizing alpha-chloro-alpha-acetyl-gamma-butyrolactone from aminopyrimidine mother liquor and co-producing methyl formate and application thereof 江苏兄弟维生素有限公司 2025-03-04 CN claimed
CN-119350184-A Process for synthesizing and co-producing alpha- (o-chloroaniline) methyl-beta-formylamino propionitrile by using chloroester and application thereof 江苏兄弟维生素有限公司 2025-01-24 CN claimed
CN-118771979-A Method for recovering alpha-acetyl-gamma-butyrolactone pre-boiling residues 顺毅宜昌化工有限公司 2024-10-15 CN claimed
CN-118724693-A Preparation method of 3, 5-dichloro-2-pentanone 潍坊中农联合化工有限公司 2024-10-01 CN claimed
CN-118373732-A Continuous synthesis method and continuous device of 2-chloro-1- (1-chlorocyclopropyl) ethanone 天津凯莱英医药科技发展有限公司 2024-07-23 CN claimed
CN-115850045-B Production method and application of gamma-chloro-gamma-acetyl propanol 江苏兄弟维生素有限公司 2024-07-19 CN claimed
CN-115925655-B Process method for synthesizing and co-producing sodium bicarbonate solution by using alpha-chloro-alpha-acetyl-gamma-butyrolactone and application thereof 江苏兄弟维生素有限公司 2024-06-21 CN claimed
CN-115850211-B Process method for synthesizing and co-producing acetamidine hydrochloride by using alpha-chloro-alpha-acetyl-gamma-butyrolactone and application thereof 江苏兄弟维生素有限公司 2024-06-21 CN claimed
CN-115010587-B Clean 1-acetyl-1-chlorocyclopropane synthesis method 辽宁众辉生物科技有限公司 2024-04-30 CN claimed
CN-107473949-B Synthesis process of 3, 5-dichloro-2-pentanone 安徽国星生物化学有限公司 2020-10-02 CN claimed
CN-103772313-B A kind of synthetic method of 4-methyl-5-(2-hydroxyethyl) thiazole ZHENG GUIFU (CN) 2015-10-14 CN claimed
CN-103387557-B Continuous synthesis process of alpha-chloro-alpha-acetyl-gamma-butyrolactone JIANGSU BROTHER VITAMINS CO LTD 2015-03-11 CN claimed
CN-103387557-A Continuous synthesis process of alpha-chloro-alpha-acetyl-gamma-butyrolactone JIANGSU BROTHER VITAMINS CO LTD 2013-11-13 CN claimed
EP-1375490-A1 Process for the production of 2-acetyl-2-chloro-gamma-butyrolactone Degussa AG (DE) 2004-01-02 EP claimed
EP-0560109-B1 Process for the preparation of 1-fluorocyclopropyl-methyl-ketone BAYER AG (DE) 1996-07-17 EP claimed
US-5336809-A Process for preparing 1-fluorocyclopropyl methyl ketone BAYER AKTIENGESELLSCHAFT (DE) 1994-08-09 US claimed
EP-0560109-A2 Process for the preparation of 1-fluorocyclopropyl-methyl-ketone BAYER AG (DE) 1993-09-15 EP claimed
EP-0037474-B1 PROCESS FOR THE PREPARATION OF 1-ACETOXY-3-CHLORO-PENTANONE-4 BASF Aktiengesellschaft (DE) 1983-04-06 EP claimed
EP-0037474-A1 Process for the preparation of 1-acetoxy-3-chloro-pentanone-4 BASF Aktiengesellschaft (DE) 1981-10-14 EP claimed