SCHEMBL8990312

SCHEMBL8990312

CC(=O)C1(F)CCOC1=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
CYP2C9 P11712 3/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 2/20 0.33
CYP2C19 P33261 2/20 0.33
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8242337 0.74 ATM (0.43) TSHR
SCHEMBL7517029 0.72 CYP2C9 (0.41) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL4252207 0.72 CYP2C9 (0.41) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL263371 0.71 ALDH1A1 (0.35) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL17199882 0.71 ALDH1A1 (0.35) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL29043212 0.71 CYP2C9 (0.36) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL4895573 0.69 ALDH1A1 (0.35) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL8593083 0.68 ALDH1A1 (0.34) ALDH1A1CYP2C9LMNACYP3A4CYP2C19
SCHEMBL576329 0.67
SCHEMBL3389445 0.67 ALDH1A1 (0.36) ALDH1A1CYP2C9LMNACYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0560109-B1 Process for the preparation of 1-fluorocyclopropyl-methyl-ketone BAYER AG (DE) 1996-07-17 EP claimed
US-5336809-A Process for preparing 1-fluorocyclopropyl methyl ketone BAYER AKTIENGESELLSCHAFT (DE) 1994-08-09 US claimed
EP-0560109-A2 Process for the preparation of 1-fluorocyclopropyl-methyl-ketone BAYER AG (DE) 1993-09-15 EP claimed
JP-6009480-A None JP disclosed
EP-4498449-A2 FLUORINATED ELECTROLYTE COMPOSITION FOR CHALCOGEN BATTERY II-VI Delaware, Inc. (US) 2025-01-29 EP disclosed
US-20250006999-A1 Fluorinated Electrolyte Composition for Chalcogen Battery JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2025-01-02 US disclosed
CN-119230953-A Fluorinated electrolyte composition for chalcogen cells II-VI特拉华股份有限公司 2024-12-31 CN disclosed
US-20200054630-A1 BENZAMIDES-CONTAINING COMPOUNDS AND THEIR USE IN THE TREATMENT OF DEPRESSION MINDIMMUNE THERAPEUTICS, INC. 2020-02-20 US disclosed
US-10238654-B2 Benzamides-containing compounds and their use in the treatment of epilepsy MINDIMMUNE THERAPEUTICS, INC. (US) 2019-03-26 US disclosed
US-10238654-B2 Benzamides-containing compounds and their use in the treatment of epilepsy MINDIMMUNE THERAPEUTICS, INC. (US) 2019-03-26 US disclosed
EP-2906546-B1 BENZAMIDES H LUNDBECK AS (DK) 2018-01-10 EP disclosed
US-20140107340-A1 Benzamides H. LUNDBECK A/S (DK) 2014-04-17 US disclosed
EP-0560109-B1 Process for the preparation of 1-fluorocyclopropyl-methyl-ketone BAYER AG (DE) 1996-07-17 EP disclosed
US-5371295-A Process for preparing 1-fluorocyclopropyl methyl ketone BAYER AKTIENGESELLSCHAFT (DE) 1994-12-06 US disclosed
US-5371295-A Process for preparing 1-fluorocyclopropyl methyl ketone BAYER AKTIENGESELLSCHAFT (DE) 1994-12-06 US disclosed
US-5336809-A Process for preparing 1-fluorocyclopropyl methyl ketone BAYER AKTIENGESELLSCHAFT (DE) 1994-08-09 US disclosed
US-5336809-A Process for preparing 1-fluorocyclopropyl methyl ketone BAYER AKTIENGESELLSCHAFT (DE) 1994-08-09 US disclosed
JP-H069480-A PREPARATION OF 1-FLUOROCYCLOPROPYL METHYL KETONE BAYER AG 1994-01-18 JP disclosed
EP-0560109-A2 Process for the preparation of 1-fluorocyclopropyl-methyl-ketone BAYER AG (DE) 1993-09-15 EP disclosed
EP-0560109-A2 Process for the preparation of 1-fluorocyclopropyl-methyl-ketone BAYER AG (DE) 1993-09-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200054630-A1 BENZAMIDES-CONTAINING COMPOUNDS AND THEIR USE IN THE TREATMENT OF DEPRESSION P2RX5, P2RX7, P2RX2 ALDH1A1 637/4885CYP2C9 713/4885LMNA 1650/4885
US-20140107340-A1 Benzamides P2RX7, TRPV1, P2RX5 ALDH1A1 1424/4885CYP2C9 1236/4885LMNA 2027/4885
US-10238654-B2 Benzamides-containing compounds and their use in the treatment of epilepsy P2RX5, P2RX7, P2RX6 ALDH1A1 767/4885CYP2C9 306/4885LMNA 1674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.