Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12083338 | 0.88 | LMNA (0.34) | CYP2C9LMNAALDH1A1 | |
| SCHEMBL12083419 | 0.86 | LMNA (0.33) | CYP2C9LMNAALDH1A1 | |
| SCHEMBL4252207 | 0.74 | CYP2C9 (0.41) | CYP2C9LMNAALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL8990312 | 0.72 | ALDH1A1 (0.35) | CYP2C9LMNAALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL17199882 | 0.72 | ALDH1A1 (0.35) | CYP2C9LMNAALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL263371 | 0.72 | ALDH1A1 (0.35) | CYP2C9LMNAALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL4895573 | 0.71 | ALDH1A1 (0.35) | CYP2C9LMNAALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL4574758 | 0.70 | — | — | |
| SCHEMBL2958233 | 0.70 | LMNA (0.36) | CYP2C9LMNA | |
| SCHEMBL8593083 | 0.69 | ALDH1A1 (0.34) | CYP2C9LMNAALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831229-B | Green synthesis method of vitamin B1 intermediate | 浙江新和成股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | claimed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | claimed |
| CN-113831229-B | Green synthesis method of vitamin B1 intermediate | 浙江新和成股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-113831229-B | Green synthesis method of vitamin B1 intermediate | 浙江新和成股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-8258345-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258345-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-09-04 | — | — | US | disclosed |
| US-20110196175-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | FMC CORPORATION | 2011-08-11 | — | — | US | disclosed |
| US-20110196175-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | FMC CORPORATION | 2011-08-11 | — | — | US | disclosed |
| US-7939685-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-10 | — | — | US | disclosed |
| US-7939685-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-10 | — | — | US | disclosed |
| US-20100185014-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | FMC CORPORATION | 2010-07-22 | — | — | US | disclosed |
| US-20100185014-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | FMC CORPORATION | 2010-07-22 | — | — | US | disclosed |
| US-7414157-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-19 | — | — | US | disclosed |
| US-7414157-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-19 | — | — | US | disclosed |
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100185014-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | CBR3, CBR1, NOXO1 | CYP2C9 137/4885LMNA 3105/4885ALDH1A1 258/4885 |
| US-20110196175-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | CBR3, CBR1, NOXO1 | CYP2C9 137/4885LMNA 3105/4885ALDH1A1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.