Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26347384 | 0.86 | BTK (0.36) | BTKNPSR1POLBALDH1A1KDM4E | |
| SCHEMBL26337257 | 0.84 | BTK (0.40) | BTKNPSR1POLBALDH1A1KDM4E | |
| SCHEMBL30320131 | 0.73 | KMT2A (0.43) | NPSR1POLBALDH1A1KDM4EMEN1 | |
| SCHEMBL25607563 | 0.73 | KMT2A (0.43) | NPSR1POLBALDH1A1KDM4EMEN1 | |
| SCHEMBL2928608 | 0.72 | CCR1 (0.40) | BTKALDH1A1KDM4EMAPT | |
| SCHEMBL22598222 | 0.71 | ALDH1A1 (0.42) | BTKNPSR1POLBALDH1A1KDM4E | |
| SCHEMBL26339436 | 0.70 | BTK (0.32) | BTK | |
| SCHEMBL24618685 | 0.69 | KCNH2 (0.35) | BTKNPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL30320172 | 0.69 | KCNH2 (0.35) | BTKNPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL31008173 | 0.69 | CCR1 (0.40) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |