SCHEMBL2928608

SCHEMBL2928608

C=Cc1cccc(CO)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.40
BTK Q06187 1/20 0.36
F2R P25116 1/20 0.33
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
HRH4 Q9H3N8 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
ALDH1A1 P00352 2/20 0.30
MTOR P42345 1/20 0.30
PMP22 Q01453 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30320172 0.84 KCNH2 (0.35) BTKPGK1PGK2ALDH1A1MTOR
SCHEMBL24618685 0.84 KCNH2 (0.35) BTKPGK1PGK2ALDH1A1MTOR
SCHEMBL9069711 0.79 CHRNB2 (0.37) BTKF2RHRH4GRIN2DGRIN3B
SCHEMBL29805514 0.79 CCR1 (0.40) CCR1F2RPGK1PGK2ALDH1A1
SCHEMBL4046367 0.79 CCR1 (0.40) CCR1BTK
SCHEMBL945430 0.79 CCR1 (0.40) CCR1F2RPGK1PGK2ALDH1A1
SCHEMBL31008173 0.79 CCR1 (0.40) CCR1BTK
SCHEMBL486201 0.77 CCR1 (0.55) CCR1PGK1PGK2HRH4GRIN2D
SCHEMBL6273480 0.77 ALDH1A1 (0.36) F2RALDH1A1SMN1; SMN2CYP3A4CYP2C9
SCHEMBL29898877 0.76 HRH1 (0.42) BTKSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108950645-B Aluminum and aluminum alloy anodic oxidation nickel-free sealing agent 上海铝通化学科技有限公司 2020-10-23 CN disclosed
CN-108493469-A A kind of cross-linking type high temperature proton exchange film and preparation method thereof 中国科学院上海有机化学研究所 2018-09-04 CN disclosed
CN-107910577-A A kind of compound high temperature proton exchange film and preparation method thereof 中国科学院上海有机化学研究所 2018-04-13 CN disclosed
EP-2229377-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS Wyeth LLC (US) 2010-09-22 EP disclosed
WO-2009076602-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS WYETH (US) 2009-06-18 WO disclosed
EP-0588229-A2 Macrocyclic chelating agents for the preparation of Technetium or Rhenium complexes CIS BIO INTERNATIONAL (FR) 1994-03-23 EP disclosed