Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26347384 | 0.86 | BTK (0.36) | BTKNPSR1MAPTHDAC4POLB | |
| SCHEMBL26337267 | 0.84 | BTK (0.35) | BTKNPSR1MAPTPOLBKMT2A | |
| SCHEMBL24742543 | 0.83 | NPSR1 (0.50) | BRD4NPSR1MAPTHDAC4MTNR1A | |
| SCHEMBL22250454 | 0.77 | P2RX7 (0.46) | BRD4NPSR1POLBKMT2AP2RX7 | |
| SCHEMBL30320131 | 0.76 | KMT2A (0.43) | NPSR1MAPTPOLBKMT2AKDM4E | |
| SCHEMBL25607563 | 0.76 | KMT2A (0.43) | NPSR1MAPTPOLBKMT2AKDM4E | |
| SCHEMBL22598222 | 0.74 | ALDH1A1 (0.42) | BTKNPSR1MAPTPOLBKMT2A | |
| SCHEMBL26339436 | 0.73 | BTK (0.32) | BTK | |
| SCHEMBL9069711 | 0.72 | CHRNB2 (0.37) | BTKMAPTCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2928608 | 0.72 | CCR1 (0.40) | BTKMAPTKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |