Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26340378 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KDM4EDDB1CRBNHPGD | |
| SCHEMBL26340042 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL26340737 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL23005309 | 0.69 | DDB1 (0.46) | ALDH1A1KDM4EDDB1CRBNHPGD | |
| SCHEMBL25771217 | 0.69 | DDB1 (0.46) | ALDH1A1KDM4EDDB1CRBNHPGD | |
| SCHEMBL2329301 | 0.61 | DDB1 (0.54) | ALDH1A1KDM4EDDB1CRBNHPGD | |
| SCHEMBL15874850 | 0.60 | DDB1 (0.53) | ALDH1A1KDM4EDDB1CRBNHPGD | |
| SCHEMBL29973239 | 0.60 | DDB1 (0.53) | ALDH1A1KDM4EDDB1CRBNHPGD | |
| SCHEMBL24815345 | 0.60 | DDB1 (0.53) | ALDH1A1KDM4EDDB1CRBNHPGD | |
| SCHEMBL4132442 | 0.60 | DDB1 (0.53) | ALDH1A1KDM4EDDB1CRBNHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303481-A1 | LONG-ACTING LOW-ADDICTION HNK DERIVATIVE AND PREPARATION METHOD THEREFOR | SHENZHEN RUIJIAN BIOTECHNOLOGY CO., LTD (CN) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303481-A1 | LONG-ACTING LOW-ADDICTION HNK DERIVATIVE AND PREPARATION METHOD THEREFOR | OPRK1, OPRL1, NTRK1 | ALDH1A1 3380/4885KDM4E 3375/4885DDB1 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.