Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742798 | 0.89 | CA1 (0.52) | CA1CA2CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL28615045 | 0.83 | ALDH1A1 (0.53) | CA1CA2CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL3290105 | 0.77 | MAPK1 (0.61) | ALDH1A1SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL537890 | 0.77 | RAB9A (0.83) | ALDH1A1SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL28330616 | 0.76 | RAB9A (0.55) | ALDH1A1SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL28609722 | 0.74 | SMN1; SMN2 (0.48) | CA1CA2CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL28609715 | 0.74 | USP8 (0.52) | CA1CA2CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL19626646 | 0.74 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL23401834 | 0.74 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL1198398 | 0.74 | RAB9A (0.65) | ALDH1A1SMN1; SMN2RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |