Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.83 |
| ▸ | MEN1 | O00255 | 5/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.83 |
| ▸ | TSHR | P16473 | 2/20 | 0.83 |
| ▸ | GFER | P55789 | 1/20 | 0.83 |
| ▸ | NPC1 | O15118 | 9/20 | 0.78 |
| ▸ | MAPT | P10636 | 7/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.78 |
| ▸ | STAT1 | P42224 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.73 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.73 |
| ▸ | RELA | Q04206 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30229798 | 0.96 | RAB9A (0.84) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14132986 | 0.91 | RAB9A (1.00) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL15727491 | 0.90 | RAB9A (0.73) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL17619525 | 0.90 | RAB9A (0.69) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28519664 | 0.88 | SMN1; SMN2 (0.67) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1143708 | 0.88 | RAB9A (1.00) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL30230060 | 0.88 | SMN1; SMN2 (0.73) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL30229682 | 0.88 | RAB9A (0.77) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28516248 | 0.88 | RAB9A (0.77) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL30229823 | 0.88 | RAB9A (0.77) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115537855-A | Method for electrochemically synthesizing 4-iodine-5-aminopyrazole compound | 阜阳师范大学 | 2022-12-30 | — | — | CN | claimed |
| CN-119661525-A | Method for constructing pyrazolo [3,4-b ] pyridine by dehydrocyclization of 5-aminopyrazole and allyl alcohol | 润华(江苏)新材料有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-11993729-B2 | Chemical mechanical polishing composition | BASF SE (DE) | 2024-05-28 | — | — | US | disclosed |
| CN-118084890-A | Isoxazoline-containing pyrazole amide compound as well as preparation method and application thereof | 安徽农业大学 | 2024-05-28 | — | — | CN | disclosed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-117684188-A | Electrochemical synthesis method of 5-aminopyrazole thioether compound | 阜阳师范大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-115074760-B | Electrochemical synthesis method of 5-aminopyrazole-4-thiocyanate compound | 阜阳师范大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-115304607-B | Pyrazolopyrimidine derivative and process for preparing same | 华南农业大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-114031556-B | Synthetic method for preparing 5-amino-N-aryl-3-arylpyrazole compound by green one-pot method | 温州大学 | 2023-03-31 | — | — | CN | disclosed |
| US-11578071-B2 | Preparation of pyrazolo[3,4-B]pyridines as antimalarials | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-02-14 | — | — | US | disclosed |
| US-4612318-A | CNS-depressant and analgesic tricyclo-[pyrazolo-[3,4-6]-pyridine] derivatives and pharmaceutical compositions thereof | GRUPPO LEPETIT S.P.A. (IT) | 1986-09-16 | — | — | US | disclosed |
| EP-0114273-A1 | New pharmacologically active pyrazolopyridines | GRUPPO LEPETIT S.p.A. (IT) | 1984-08-01 | — | — | EP | disclosed |
| EP-0104522-A2 | New pyrazolo(3,4-b)pyridine derivatives and process for producing them | GRUPPO LEPETIT S.p.A. (IT) | 1984-04-04 | — | — | EP | disclosed |
| US-4234594-A | Pyrazolyl amino imidazolines as antihypertensive agents | ABBOTT LABORATORIES (US) | 1980-11-18 | — | — | US | disclosed |
| US-4226773-A | Pyrazolyl amino imidazolines as diuretic agents | ABBOTT LABORATORIES (US) | 1980-10-07 | — | — | US | disclosed |
| US-4171367-A | ANTIINFLAMMATORY | ABBOTT LABORATORIES (US) | 1979-10-16 | — | — | US | disclosed |
| US-4113718-A | Basic azo dyes | CIBA-GEIGY CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |
| US-4022799-A | DYEING, PRINTING OF NATURAL AND SYNTHETIC MATERIALS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |
| US-4001253-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3950347-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578071-B2 | Preparation of pyrazolo[3,4-B]pyridines as antimalarials | PNPO, NOX3, G6PD | RAB9A 1213/4885SMN1; SMN2 4360/4885ALDH1A1 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.