Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.60 |
| ▸ | APLNR | P35414 | 1/20 | 0.60 |
| ▸ | CCR6 | P51684 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26342422 | 0.85 | MEN1 (0.62) | LMNAALDH1A1HTTSMN1; SMN2CXCR5 | |
| SCHEMBL26342419 | 0.82 | SMN1; SMN2 (0.62) | LMNAALDH1A1HTTSMN1; SMN2CXCR5 | |
| SCHEMBL26341684 | 0.81 | ALDH1A1 (0.62) | LMNAALDH1A1HTTSMN1; SMN2CXCR5 | |
| SCHEMBL27706390 | 0.81 | MAPT (0.56) | LMNAALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL22445661 | 0.80 | KMT2A (0.56) | LMNAALDH1A1HTTSMN1; SMN2CXCR5 | |
| SCHEMBL14132421 | 0.79 | LMNA (0.70) | LMNAALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL26341419 | 0.79 | ALDH1A1 (0.68) | LMNAALDH1A1HTTSMN1; SMN2CXCR5 | |
| SCHEMBL27694051 | 0.78 | LMNA (0.53) | LMNAALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL16112358 | 0.78 | LMNA (0.72) | LMNAALDH1A1HTTSMN1; SMN2CXCR5 | |
| SCHEMBL14132564 | 0.76 | GRM5 (0.91) | LMNASMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |