Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27706390 | 0.89 | MAPT (0.56) | LMNAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL27706388 | 0.88 | GRN (0.56) | LMNAPRCPMAPTMEN1KMT2A | |
| SCHEMBL27706437 | 0.81 | SMN1; SMN2 (0.63) | LMNAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL26342427 | 0.78 | LMNA (0.72) | LMNAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL24035609 | 0.76 | LMNA (0.69) | LMNAPRCPCYP1A2CYP2C9TP53 | |
| SCHEMBL27687135 | 0.76 | MARS1 (0.65) | LMNAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL2565517 | 0.76 | ALDH1A1 (0.56) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27860360 | 0.75 | ALDH1A1 (0.55) | LMNAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4689445 | 0.73 | GRN (0.66) | LMNAMAPTTP53MDM2SMN1; SMN2 | |
| SCHEMBL2546138 | 0.72 | PHGDH (0.65) | LMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101121711-A | Pyrazolcarbazone derivatives and application thereof | UNIV SHANDONG (CN) | 2008-02-13 | — | — | CN | disclosed |