SCHEMBL26343151

SCHEMBL26343151

Cc1cc(NC(=O)CN2CCN(c3ccccn3)CC2)ccn1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.77
DRD4 P21917 4/20 0.77
DRD3 P35462 3/20 0.77
THRB P10828 1/20 0.73
NPSR1 Q6W5P4 1/20 0.73
ALDH1A1 P00352 6/20 0.71
LMNA P02545 4/20 0.71
TSHR P16473 2/20 0.71
KMT2A Q03164 8/20 0.70
MEN1 O00255 7/20 0.70
ATM Q13315 1/20 0.70
HSD17B10 Q99714 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
GFER P55789 1/20 0.66
MAPT P10636 3/20 0.64
KDM4E B2RXH2 2/20 0.64
GAA P10253 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.63
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4003932 0.87 DRD2 (1.00) DRD2DRD4DRD3THRBNPSR1
SCHEMBL26343148 0.86 MEN1 (0.69) DRD2DRD4DRD3ALDH1A1LMNA
SCHEMBL4008925 0.85 THRB (1.00) DRD2DRD4DRD3THRBNPSR1
SCHEMBL11001390 0.83 DRD2 (0.68) DRD2DRD4DRD3THRBNPSR1
SCHEMBL4006361 0.83 DRD2 (0.71) DRD2DRD4DRD3THRBNPSR1
SCHEMBL4007645 0.82 ALDH1A1 (0.78) DRD2DRD4DRD3THRBNPSR1
SCHEMBL4006313 0.82 THRB (0.77) DRD2DRD4DRD3THRBNPSR1
SCHEMBL26343157 0.82 MEN1 (0.56) DRD2DRD4DRD3ALDH1A1LMNA
SCHEMBL4010416 0.81 POLB (0.84) DRD2DRD4DRD3THRBNPSR1
SCHEMBL4006366 0.81 THRB (0.82) DRD2DRD4DRD3THRBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303493-A1 ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303493-A1 ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF CAPG, SLC11A2, CAPRIN1 DRD2 4359/4885DRD4 4279/4885DRD3 4219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.