Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE8A | O60658 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459661 | 1.00 | PDE9A (0.39) | PDE9AALDH1A1POLBPGRHTT | |
| SCHEMBL29588826 | 0.91 | CHRM2 (0.43) | PDE9AMAPK1OPRM1OPRL1NTRK1 | |
| SCHEMBL26344207 | 0.91 | CHRM2 (0.43) | PDE9AMAPK1OPRM1OPRL1NTRK1 | |
| SCHEMBL26662006 | 0.91 | CHRM2 (0.43) | PDE9AMAPK1OPRM1OPRL1NTRK1 | |
| SCHEMBL30637047 | 0.90 | CHRM2 (0.42) | PDE9AMAPK1OPRM1OPRL1NTRK1 | |
| Calcium SCHEMBL30637044 | 0.90 | CHRM2 (0.42) | PDE9AMAPK1OPRM1OPRL1NTRK1 | |
| Diethylamine SCHEMBL30637040 | 0.86 | CHRM2 (0.39) | PDE9APDE2APDE10AMAPK1OPRM1 | |
| SCHEMBL26346052 | 0.84 | ALDH1A1 (0.38) | PDE9AALDH1A1POLBPGRHTT | |
| SCHEMBL30459378 | 0.80 | PGR (0.37) | PDE9APGRPDE2APDE4DCYP3A4 | |
| SCHEMBL26344167 | 0.80 | PGR (0.37) | PDE9APGRPDE2APDE4DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |