Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.37 |
| ▸ | KRAS | P01116 | 2/20 | 0.37 |
| ▸ | PDE9A | O76083 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26344207 | 1.00 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL29588826 | 1.00 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30637047 | 0.99 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Calcium SCHEMBL30637044 | 0.99 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Diethylamine SCHEMBL30637040 | 0.95 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30459661 | 0.91 | PDE9A (0.39) | NTRK1PDE9AMAPK1OPRM1OPRL1 | |
| SCHEMBL26344218 | 0.91 | PDE9A (0.39) | NTRK1PDE9AMAPK1OPRM1OPRL1 | |
| SCHEMBL30811374 | 0.85 | IDH1 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL26345799 | 0.84 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL26345985 | 0.80 | PDE2A (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326743-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) | 2025-10-23 | — | — | US | claimed |
| EP-4527837-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2025-03-26 | — | — | EP | claimed |
| CN-119053591-A | Crystal form of triazinedione derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2024-11-29 | — | — | CN | claimed |
| WO-2023222103-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏恒瑞医药股份有限公司 | 2023-11-23 | — | — | WO | claimed |
| US-20250326743-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) | 2025-10-23 | — | — | US | disclosed |
| US-20250326743-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) | 2025-10-23 | — | — | US | disclosed |
| EP-4527837-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2025-03-26 | — | — | EP | disclosed |
| EP-4527837-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2025-03-26 | — | — | EP | disclosed |
| CN-119053591-A | Crystal form of triazinedione derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| WO-2023222103-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏恒瑞医药股份有限公司 | 2023-11-23 | — | — | WO | disclosed |
| WO-2023222103-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏恒瑞医药股份有限公司 | 2023-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326743-A1 | CRYSTAL FORMS OF TRIAZINE DIONE DERIVATIVE AND PREPARATION METHOD THEREFOR | WEE1, WEE2, THEM6 | CHRM2 4742/4885CHRM4 4705/4885CHRM5 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.