SCHEMBL26344232

SCHEMBL26344232

Cc1nc2ccccc2n1-c1ccc(-c2c3ccccc3c(-c3ccccc3-c3ccncc3)c3ccccc23)cc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.51
MAPK1 P28482 1/20 0.51
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 2/20 0.41
HSP90AA1 P07900 1/20 0.40
MAPT P10636 1/20 0.40
TSHR P16473 1/20 0.40
GSR P00390 1/20 0.39
PDE10A Q9Y233 1/20 0.38
RAB9A P51151 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
GRIA1 P42261 1/20 0.37
CACNG8 Q8WXS5 1/20 0.37
CACNG2 Q9Y698 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2604819 0.92 MAPK1 (0.58) HTTMAPK1ALDH1A1MAPTTSHR
SCHEMBL21392515 0.92 MAPK1 (0.57) HTTMAPK1MEN1KMT2AALDH1A1
SCHEMBL2604834 0.91 MAPK1 (0.57) HTTMAPK1MEN1KMT2AALDH1A1
SCHEMBL21392415 0.89 MAPK1 (0.61) HTTMAPK1ALDH1A1MAPTTSHR
SCHEMBL26344436 0.88 MAPK1 (0.48) HTTMAPK1MEN1KMT2AMAPT
SCHEMBL26344217 0.88 PDE10A (0.42) HTTMAPK1MEN1KMT2AALDH1A1
SCHEMBL26344227 0.88 MAPK1 (0.48) HTTMAPK1MEN1KMT2AALDH1A1
SCHEMBL26344220 0.87 ESR1 (0.53) HTTMAPK1MEN1KMT2AALDH1A1
SCHEMBL26345057 0.87 MEN1 (0.45) HTTMAPK1MEN1KMT2AALDH1A1
SCHEMBL26344233 0.87 PDE10A (0.42) HTTMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 HTT 2655/4885MAPK1 675/4885MEN1 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.