SCHEMBL21392515

SCHEMBL21392515

Cc1nc2ccccc2n1-c1ccc(-c2c3ccccc3c(-c3ccc(-c4ccncc4)cc3)c3ccccc23)cc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.57
HTT P42858 1/20 0.57
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPT P10636 2/20 0.47
HSP90AA1 P07900 1/20 0.47
ALDH1A1 P00352 2/20 0.45
TSHR P16473 1/20 0.44
GSR P00390 1/20 0.43
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
POLB P06746 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GRIA1 P42261 1/20 0.40
CACNG8 Q8WXS5 1/20 0.40
CACNG2 Q9Y698 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26344381 0.93 MAPK1 (0.50) MAPK1HTTMEN1KMT2AMAPT
SCHEMBL26344232 0.92 HTT (0.51) MAPK1HTTMEN1KMT2AMAPT
SCHEMBL2604833 0.91 MAPK1 (0.67) MAPK1HTTMEN1KMT2AMAPT
SCHEMBL2604820 0.91 MAPK1 (0.67) MAPK1HTTMEN1KMT2AMAPT
SCHEMBL26345071 0.90 MEN1 (0.47) MAPK1HTTMEN1KMT2AMAPT
SCHEMBL26344568 0.89 MAPK1 (0.51) MAPK1HTTMEN1KMT2AMAPT
SCHEMBL15964463 0.89 MAPK1 (0.69) MAPK1HTTMEN1KMT2AMAPT
SCHEMBL21392683 0.89 MAPK1 (0.49) MAPK1HTTMEN1KMT2AMAPT
SCHEMBL14499559 0.88 MAPK1 (0.62) MAPK1HTTMAPTALDH1A1TSHR
SCHEMBL21392517 0.88 MAPK1 (0.52) MAPK1HTTMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed
US-20190296238-A1 Organic Light-emitting Element LG CHEM, LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296238-A1 Organic Light-emitting Element CRY1, CRY2, NR2E3 MAPK1 4606/4885HTT 2428/4885MEN1 1414/4885
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 MAPK1 675/4885HTT 2655/4885MEN1 480/4885
US-11877509-B2 Organic light-emitting element CRY1, CRY2, NR2E3 MAPK1 4606/4885HTT 2428/4885MEN1 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.