Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34262 | 1.00 | KIF11 (0.50) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3792783 | 1.00 | KIF11 (0.50) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27148055 | 1.00 | KIF11 (0.50) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28482917 | 1.00 | KIF11 (0.50) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18670133 | 1.00 | KIF11 (0.50) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28487494 | 1.00 | KIF11 (0.50) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15144366 | 1.00 | KIF11 (0.50) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3087541 | 0.98 | KIF11 (0.52) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL329636 | 0.93 | ALDH1A1 (0.55) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23405872 | 0.90 | KIF11 (0.50) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793106-A | Polypeptide helix conformation stabilizing method | 安徽大学 | 2020-10-20 | — | — | CN | claimed |
| CN-111793106-A | Polypeptide helix conformation stabilizing method | 安徽大学 | 2020-10-20 | — | — | CN | disclosed |
| EP-2437786-B1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RES & DEV (IL) | 2016-05-18 | — | — | EP | disclosed |
| US-20150093370-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-04-02 | — | — | US | disclosed |
| US-20120134977-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2012-05-31 | — | — | US | disclosed |
| EP-2437786-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | Yeda Research and Development Co. Ltd. (IL) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010140148-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO . LTD (IL) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120134977-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | ALB, DNPEP, CNDP2 | KIF11 4455/4885HDAC3 2780/4885HDAC4 3522/4885 |
| US-20150093370-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | ALB, DNPEP, CNDP2 | KIF11 4455/4885HDAC3 2780/4885HDAC4 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.