Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 17/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087541 | 0.95 | KIF11 (0.52) | ALDH1A1KIF11HDAC3MAPK1ADRA1A | |
| SCHEMBL2634426 | 0.93 | KIF11 (0.50) | ALDH1A1KIF11HDAC3MAPK1ADRA1A | |
| SCHEMBL15144366 | 0.93 | KIF11 (0.50) | ALDH1A1KIF11HDAC3MAPK1ADRA1A | |
| SCHEMBL27148055 | 0.93 | KIF11 (0.50) | ALDH1A1KIF11HDAC3MAPK1ADRA1A | |
| SCHEMBL34262 | 0.93 | KIF11 (0.50) | ALDH1A1KIF11HDAC3MAPK1ADRA1A | |
| SCHEMBL28487494 | 0.93 | KIF11 (0.50) | ALDH1A1KIF11HDAC3MAPK1ADRA1A | |
| SCHEMBL28482917 | 0.93 | KIF11 (0.50) | ALDH1A1KIF11HDAC3MAPK1ADRA1A | |
| SCHEMBL18670133 | 0.93 | KIF11 (0.50) | ALDH1A1KIF11HDAC3MAPK1ADRA1A | |
| SCHEMBL3792783 | 0.93 | KIF11 (0.50) | ALDH1A1KIF11HDAC3MAPK1ADRA1A | |
| SCHEMBL34785 | 0.89 | KIF11 (0.57) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793106-A | Polypeptide helix conformation stabilizing method | 安徽大学 | 2020-10-20 | — | — | CN | claimed |
| US-20230293522-A1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-09-21 | — | — | US | disclosed |
| US-11661398-B2 | Cellular transport system for transferring a sulfonic acid construct carrying a cargo into the cytoplasm of a cell | Scientist of Fortune, S.A. (LU) | 2023-05-30 | — | — | US | disclosed |
| US-20220331316-A1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2022-10-20 | — | — | US | disclosed |
| EP-3901159-A1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| CN-106999479-B | Heteroaryl compounds useful as inhibitors of SUMO activating enzyme | 米伦纽姆医药公司 | 2021-07-16 | — | — | CN | disclosed |
| EP-3517112-B1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARM INC (US) | 2021-04-07 | — | — | EP | disclosed |
| US-20210009513-A1 | CELLULAR TRANSPORT SYSTEM FOR TRANSFERRING A SULFONIC ACID CONSTRUCT CARRYING A CARGO INTO THE CYTOPLASM OF A CELL | Scientist of Fortune, S.A. (LU) | 2021-01-14 | — | — | US | disclosed |
| CN-111793106-A | Polypeptide helix conformation stabilizing method | 安徽大学 | 2020-10-20 | — | — | CN | disclosed |
| US-10780090-B2 | Heteroaryl compounds useful as inhibitors of SUMO activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2020-09-22 | — | — | US | disclosed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| EP-1988911-A2 | COMPOSITIONS AND METHODS FOR TRANSPORT OF MOLECULES WITH ENHANCED RELEASE PROPERTIES ACROSS BIOLOGICAL BARRIERS | The Board Of Trustees Of The University Of the Leland Stanford Junior University (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2008069824-A2 | COMPOSITIONS AND METHODS FOR TRANSPORT OF MOLECULES WITH ENHANCED RELEASE PROPERTIES ACROSS BIOLOGICAL BARRIERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2008-06-12 | — | — | WO | disclosed |
| US-7291673-B2 | Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds | EIDGENOSSICHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2007-11-06 | — | — | US | disclosed |
| EP-1292709-A4 | CONJUGATE ADDITION REACTIONS FOR THE CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS | EIDGENOESS TECH HOCHSCHULE (CH) | 2004-09-22 | — | — | EP | disclosed |
| US-20030220245-A1 | Conjugate addition reactions for the controlled delivery of pharmaceutical active compounds | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2003-11-27 | — | — | US | disclosed |
| EP-1292709-A1 | CONJUGATE ADDITION REACTIONS FOR THE CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS | Eidgenössische Technische Hochschule Zürich (CH) | 2003-03-19 | — | — | EP | disclosed |
| EP-1200131-A2 | COMPOSITIONS AND METHODS FOR TARGETED ENZYMATIC RELEASE OF CELL REGULATORY COMPOUNDS | Marker Gene Technologies, Inc. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001092584-A1 | CONJUGATE ADDITION REACTIONS FOR THE CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2001-12-06 | — | — | WO | disclosed |
| WO-2001002020-A2 | COMPOSITIONS AND METHODS FOR TARGETED ENZYMATIC RELEASE OF CELL REGULATORY COMPOUNDS | MARKER GENE TECHNOLOGIES, INC. (US) | 2001-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661398-B2 | Cellular transport system for transferring a sulfonic acid construct carrying a cargo into the cytoplasm of a cell | GOT1, GGCT, TGM2 | ALDH1A1 1289/4885KIF11 2263/4885HDAC3 3164/4885 |
| US-20230293522-A1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | SAE1, SUMO1, SUMO3 | ALDH1A1 1512/4885KIF11 4157/4885HDAC3 298/4885 |
| US-20210009513-A1 | CELLULAR TRANSPORT SYSTEM FOR TRANSFERRING A SULFONIC ACID CONSTRUCT CARRYING A CARGO INTO THE CYTOPLASM OF A CELL | GOT1, GGCT, TGM2 | ALDH1A1 1289/4885KIF11 2263/4885HDAC3 3164/4885 |
| US-10780090-B2 | Heteroaryl compounds useful as inhibitors of SUMO activating enzyme | SAE1, SUMO1, SUMO3 | ALDH1A1 1512/4885KIF11 4157/4885HDAC3 298/4885 |
| US-20220331316-A1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | SAE1, SUMO1, SUMO3 | ALDH1A1 1512/4885KIF11 4157/4885HDAC3 298/4885 |
| US-20030220245-A1 | Conjugate addition reactions for the controlled delivery of pharmaceutical active compounds | PAICS, C9, LIPA | ALDH1A1 533/4885KIF11 2222/4885HDAC3 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.