SCHEMBL26344505

SCHEMBL26344505

c1ccc(-c2nc3ccccc3n2-c2ccccc2-c2c3ccccc3c(-c3cccc(-c4cccnc4)c3)c3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.44
CYP11B2 P19099 2/20 0.41
MDM2 Q00987 1/20 0.40
G6PD P11413 2/20 0.39
DHODH Q02127 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
NOS2 P35228 1/20 0.37
RAD51 Q06609 1/20 0.37
POLB P06746 1/20 0.37
AOC3 Q16853 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26344532 0.92 MDM2 (0.43) MAPTCYP11B2MDM2G6PDDHODH
SCHEMBL26343743 0.90 ESR1 (0.44) MAPTESR1ESR2KDM4EALDH1A1
SCHEMBL26344509 0.90 TSHR (0.44) MAPTCYP11B2DHODHKDM4EALDH1A1
SCHEMBL26344432 0.89 MAPT (0.45) MAPTCYP11B2MDM2G6PDESR1
SCHEMBL26345130 0.87 MAPT (0.47) MAPTCYP11B2MDM2G6PDESR1
SCHEMBL26344492 0.87 MAPT (0.39) MAPTCYP11B2KDM4EALDH1A1HPGD
SCHEMBL26344507 0.86 MAPT (0.54) MAPTCYP11B2MDM2G6PDESR1
SCHEMBL26345265 0.86 ESR1 (0.41) MAPTESR1ESR2KDM4EALDH1A1
SCHEMBL26344503 0.85 MAPT (0.51) MAPTCYP11B2MDM2G6PDESR1
SCHEMBL26343675 0.84 ESR1 (0.45) MAPTESR1ESR2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 MAPT 1419/4885CYP11B2 2732/4885MDM2 3751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.