SCHEMBL26344432

SCHEMBL26344432

c1ccc(-c2nc3ccccc3n2-c2ccccc2-c2c3ccccc3c(-c3ccccc3-c3cccnc3)c3ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.45
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
CYP11B2 P19099 2/20 0.44
POLB P06746 1/20 0.43
MDM2 Q00987 1/20 0.42
G6PD P11413 2/20 0.42
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
RAD51 Q06609 1/20 0.40
AOC3 Q16853 1/20 0.40
MEN1 O00255 1/20 0.39
HSP90AA1 P07900 1/20 0.39
KMT2A Q03164 1/20 0.39
LCK P06239 1/20 0.39
CYP11B1 P15538 1/20 0.39
LMNA P02545 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26344532 0.91 MDM2 (0.43) MAPTESR1ESR2CYP11B2POLB
SCHEMBL26345127 0.90 CYP11B2 (0.47) MAPTESR1ESR2CYP11B2MDM2
SCHEMBL26343568 0.89 ESR1 (0.48) MAPTESR1ESR2POLBKDM4E
SCHEMBL26344505 0.89 MAPT (0.44) MAPTESR1ESR2CYP11B2POLB
SCHEMBL26344435 0.89 TSHR (0.48) MAPTCYP11B2G6PDKDM4EALDH1A1
SCHEMBL26344224 0.88 KMT2A (0.46) MAPTESR1ESR2POLBMDM2
SCHEMBL26344429 0.87 ESR1 (0.51) MAPTESR1ESR2CYP11B2MDM2
SCHEMBL26344427 0.87 ESR1 (0.54) MAPTESR1ESR2CYP11B2MDM2
SCHEMBL26343480 0.85 ESR1 (0.49) MAPTESR1ESR2POLBKDM4E
SCHEMBL26344425 0.85 RECQL (0.51) MAPTESR1ESR2CYP11B2MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 MAPT 1419/4885ESR1 124/4885ESR2 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.