SCHEMBL26344912

SCHEMBL26344912

Cc1nc2ccccc2n1-c1c2ccccc2c(-c2ccc3c(c2)C(C)(C)c2ccccc2-3)c2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.39
MAPK1 P28482 2/20 0.39
TSHR P16473 3/20 0.38
PIK3CD O00329 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
PIK3CG P48736 1/20 0.36
FLT3 P36888 2/20 0.35
MAPT P10636 3/20 0.34
POLB P06746 3/20 0.34
LMNA P02545 2/20 0.34
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34
GAA P10253 1/20 0.34
RAB9A P51151 2/20 0.33
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
HSD11B1 P28845 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21392542 0.90 MAPK1 (0.47) HTTMAPK1TSHRPOLBHSD17B10
SCHEMBL26344989 0.89 ESR1 (0.39) HTTMAPK1TSHRFLT3MAPT
SCHEMBL26343708 0.89 TSHR (0.44) HTTMAPK1TSHRPIK3CDPIK3CA
SCHEMBL22706780 0.89 TSHR (0.43) HTTMAPK1TSHRPIK3CDPIK3CA
SCHEMBL26343707 0.89 MAPK1 (0.45) HTTMAPK1TSHRFLT3POLB
SCHEMBL26344938 0.89 MAPT (0.38) MAPK1TSHRFLT3MAPTLMNA
SCHEMBL26344965 0.84 RECQL (0.42) HTTMAPK1FLT3MAPTRAB9A
SCHEMBL26367252 0.83 PDK2 (0.31)
SCHEMBL24811914 0.83 ESR1 (0.44) HTTMAPK1MAPTPOLBLMNA
SCHEMBL26354827 0.83 FLT3 (0.32) HTTFLT3MAPTLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 HTT 2655/4885MAPK1 675/4885TSHR 4213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.